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Medication, Exercise and Physiotherapy

For most types of pain, the first step of treatment is a review of your medicines, exercise and physiotherapy. This page explains how pain and nerve-pain medicines are reviewed, how an exercise programme is built, what to expect and when it is time to consider the next step.

  • Last updated:
  • Medical editor: Prof. Dr. Hüsnü Süslü

At a glance

Treatment period
Usually several weeks; progress is reviewed at follow-up visits
Anaesthesia
Not needed
Hospital stay
Not needed; treatment continues as an outpatient and at home
Return to daily life
Usually carried out alongside your normal daily activities

Timings are for general information; your individual plan is made after your examination.

Who may benefit?

  • People with recent or ongoing back, neck or joint-related pain
  • People with leg or arm pain from a lumbar or cervical disc herniation, without weakness
  • People with nerve pain (neuropathic pain) felt as burning, tingling or electric shocks
  • People with fibromyalgia or widespread muscle (myofascial) pain
  • People with long-standing pain whose medicines, doses or side effects need reviewing
  • People returning to an exercise programme after an image-guided procedure

Who may not be suitable?

  • People with signs of cauda equina syndrome, such as loss of bladder or bowel control or numbness around the genitals: this needs emergency surgical assessment
  • People with rapidly worsening weakness, or signs of pressure on the spinal cord in the neck such as clumsy hands or unsteady walking: this needs urgent surgical assessment
  • People with pain together with fever, unexplained weight loss, a history of cancer or a recent serious fall or accident: other causes are investigated first
  • People whose pain has not eased enough after several weeks of appropriate treatment: this step alone may not be enough, and image-guided options are considered
  • For some medicines: kidney, liver, stomach or heart disease, pregnancy or breastfeeding can limit the choice

How is it planned?

  1. How your pain started and changed, the treatments you have tried and every medicine you take are discussed in detail.

  2. A physical and neurological examination is carried out; imaging or blood tests are requested if needed.

  3. Your medicines are reviewed for the type of pain you have: unnecessary or interacting medicines are simplified, and a new medicine is usually started at a low dose.

  4. An exercise programme that gradually becomes more demanding is planned, with a physiotherapist or to do at home.

  5. You are given personal advice on posture, work habits, sleep and daily activities.

  6. At follow-up visits, changes in pain, sleep and daily function are reviewed; if the response is not enough, the next step is discussed.

What is it?

For most types of pain, the first step is not a procedure but a plan: reviewing your medicines, regular exercise, physiotherapy and advice on daily habits. Doctors call this conservative treatment, meaning care without surgery or interventional procedures.

This step is the foundation of treatment for many conditions, including low back pain, neck pain, sciatica caused by a disc herniation, neuropathic pain and fibromyalgia.

When is it considered?

Without emergency signs or worsening weakness, treatment for most new episodes of pain starts here. Back and neck pain often eases within weeks; meanwhile the aim is to control the pain while keeping you moving.

This step matters for long-standing (chronic) pain too: medicines that no longer help or interact with each other are simplified, and muscles weakened by inactivity are rebuilt with a gradual programme.

How are medicines reviewed?

The choice of medicine depends on the type of pain: pain from muscles and joints responds to different medicines than nerve pain. The aim is not to remove pain completely, but to reduce it enough for you to keep up with exercise and daily life. The groups below are for general information only; your doctor decides on the medicine, dose and duration after examining you.

Pain relievers and anti-inflammatory medicines

Non-steroidal anti-inflammatory drugs (NSAIDs) are commonly used for back and joint pain. Because they can affect the stomach, kidneys, heart and blood vessels, they are taken at the lowest effective dose for as short a time as possible. Whether you also need stomach protection depends on your age and other health conditions.

Nerve-pain medicines

For nerve pain, often described as burning, tingling, stabbing or like an electric shock, some medicines from the antidepressant and anti-epileptic groups are used. Here they are given not to treat depression or epilepsy, but to change the way the nervous system processes pain signals. They are usually started at a low dose and increased gradually while side effects are monitored. For leg pain caused by a disc herniation (sciatica), a clear benefit has not been shown and some guidelines advise against them; whether to use them is decided together at your consultation.

Muscle relaxants, skin treatments and opioids

Muscle relaxants may be used briefly in selected cases but can cause drowsiness. For pain in one small area, creams or patches may be an option. Guidelines advise against opioids for long-standing low back pain; for a severe new episode they may be used briefly in selected cases, with close monitoring. Cancer pain is managed differently.

Each medicine is reviewed at follow-up visits; those that are not helping are reduced and stopped in a planned way.

Exercise and physiotherapy

Guidelines recommend regular, structured exercise as a core part of treatment for long-standing back and neck pain. The programme is tailored to you and may include strengthening and stretching, aerobic exercise such as walking or swimming, and mind-body approaches such as yoga or Pilates.

A physiotherapist builds the programme around your pain and fitness, checks your technique and increases the challenge step by step. Manual therapy may be added where appropriate, but alongside exercise rather than instead of it. Heat or cold can give short-term relief. Device-based treatments such as electrical nerve stimulation (TENS) or therapeutic ultrasound are not recommended by guidelines for low back pain.

Posture, activity and sleep

  • Stay active: prolonged bed rest can slow recovery. Carry on with daily activities as far as the pain allows.
  • Avoid staying in one position for long: if you work at a desk, get up and walk for a few minutes every 30-60 minutes.
  • Pace your activities: rather than doing too much on good days and very little on bad ones, spread tasks through the day.
  • Lift with care: keep the load close to your body, bend your knees and avoid twisting while you lift.
  • Look after your sleep: keep regular hours and cut down on caffeine and screens in the evening; pain and sleep affect each other.

With long-standing pain, stress, anxiety and low mood can make pain feel stronger; psychological support may then become part of the plan.

When might you notice results?

With a new episode of back or neck pain, relief often comes within days to a few weeks. The benefit of exercise builds more slowly, over several weeks, and because nerve-pain medicines are increased gradually, it can take a few weeks to tell whether one is working.

Results vary from person to person. Mild soreness is common when you start exercising; if pain is sharp, spreads or worsens each time, the programme is adjusted.

When is the next step considered?

Image-guided interventional treatments are considered when:

  • pain has not eased enough after several weeks of appropriate medication and exercise
  • pain continues to clearly limit sleep, work or daily life
  • pain makes it impossible to keep up with the exercise programme
  • medicines cannot be used because of side effects

For severe pain travelling down the leg, an epidural steroid injection may be an option; for pain from the small joints of the spine, a facet joint injection and radiofrequency treatment may be considered. For an overview of lumbar disc options, see non-surgical lumbar disc treatment. Exercise continues after a procedure too: the procedure is there to help you get back to it.

If there is weakness or worsening nerve findings, a surgical opinion is sought. Our guide When is herniated disc surgery needed? explains when an operation is considered.

Symptoms that need urgent attention

Also see a doctor without delay if you have:

  • pain together with fever or unexplained weight loss, or new back pain with a history of cancer
  • severe pain that started after a fall or accident
  • black, tarry stools, which can be a sign of stomach bleeding caused by pain relievers

To work out the right plan for you, you can request a consultation.

Before your visit

  • Bring a list of all your medicines, including herbal products and supplements
  • Note which medicines you have tried before, whether they helped and any side effects
  • Bring any MRI scans, X-rays and reports you have
  • For a few days before your visit, note how strong your pain is, when it gets worse and how it affects your sleep
  • Tell the team about any kidney, liver, stomach or heart condition, and whether you are pregnant or breastfeeding

Possible risks and side effects

Medicines and exercise can have side effects too. Your individual risks are discussed during the consultation.

  • With some pain relievers: stomach upset, a risk of stomach bleeding or strain on the kidneys
  • With nerve-pain medicines: drowsiness, dizziness, weight change or a dry mouth
  • With muscle relaxants: drowsiness and reduced concentration, which can affect driving
  • With opioid pain relievers: constipation, nausea, drowsiness and, with long-term use, tolerance or dependence
  • Temporary muscle soreness or a short-lived increase in pain in the first weeks of exercise
  • Pain that does not ease enough, so that the next step of treatment is needed

Used for

  • Low Back PainLow back pain is pain felt between the lower edge of the ribs and the creases of the buttocks. Most adults experience it at some point; it often eases within a few weeks, and when it lasts longer, pinpointing its source guides treatment.
  • Lumbar Disc HerniationA lumbar disc herniation occurs when the soft centre of a spinal disc pushes through a tear in its tougher outer ring and presses on, or irritates, a nearby nerve root. It can cause back pain and, more typically, pain, numbness or weakness down the leg; in many people symptoms ease over time without surgery.
  • SciaticaSciatica is nerve pain that travels from the lower back into the buttock and down the back of the leg. It is a symptom rather than a disease, most often showing that a disc herniation or narrowing around a nerve root is affecting the nerve.
  • Neck PainNeck pain is felt anywhere from the base of the skull to the shoulders and is very common, usually linked to muscle strain, posture or age-related changes. Most episodes ease within a few weeks; when pain persists, identifying its source becomes important.
  • Cervical Disc HerniationA cervical disc herniation occurs when the soft centre of a disc in the neck pushes out and presses on a nerve root or the spinal cord. As well as neck pain, it can cause pain, numbness and weakness spreading into the arm and fingers.
  • Neuropathic PainNeuropathic pain is caused by damage to, or disease of, the nerves that carry sensations such as touch, temperature and pain. It typically burns, shoots or tingles, and often responds poorly to standard painkillers.
  • FibromyalgiaFibromyalgia is a long-term condition in which widespread pain comes with tiredness, unrefreshing sleep and difficulty concentrating, linked to changes in the way the nervous system processes pain. It does not damage the muscles or joints, and exercise, good sleep habits and pain-coping skills form the basis of treatment.
  • Myofascial Pain SyndromeMyofascial pain syndrome is a regional muscle pain caused by tender trigger points within the muscles. It most often affects the neck, shoulder and lower back muscles, and is treated by improving posture and working habits, physiotherapy and, when needed, trigger point injections.

Frequently asked questions

Is it harmful to take pain relievers for a long time?

Some pain relievers can affect the stomach, kidneys or heart with long-term use, and some can cause dependence. That is why medicines are reviewed regularly. Do not increase the dose yourself, and do not stop a medicine suddenly without talking to your doctor.

Should I exercise while I am in pain?

In most cases, yes, with a programme adapted to your pain. Mild soreness at the start is common. If the pain becomes sharp or spreads, or you develop new weakness, pause the exercises and contact your doctor.

If I am given an antidepressant for nerve pain, does that mean I am depressed?

No. Some antidepressants are used for nerve pain because they change the way the nervous system processes pain signals. The aim is to treat the pain, not depression.

What happens if medication and exercise are not enough?

If pain has not eased enough after several weeks of appropriate treatment, image-guided treatments such as an epidural or facet joint injection may be considered. If there is weakness or worsening nerve findings, a surgical opinion is sought.

References

  1. 1.Low back pain and sciatica in over 16s: assessment and management (NG59)NICE
  2. 2.Neuropathic pain in adults: pharmacological management in non-specialist settings (CG173)NICE
  3. 3.Chronic pain (primary and secondary) in over 16s: assessment of all chronic pain and management of chronic primary pain (NG193)NICE
  4. 4.WHO guideline for non-surgical management of chronic primary low back pain in adults in primary and community care settingsWorld Health Organization (2023)
  5. 5.Exercise therapy for chronic low back painCochrane Database of Systematic Reviews (2021)
  6. 6.Pharmacotherapy for neuropathic pain in adults: a systematic review and meta-analysisThe Lancet Neurology (2015)
  7. 7.Back painNHS

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